Genetrace DNA Celiac Disease Test
$248.99$269.99
Nearly everyone with celiac disease carry at least one genetic risk variant linked to an increased risk of celiac disease. Find out your risk with this DNA test.
Alleles Tested:
- HLA-DQA1*05
- HLA-DQB1*02
- HLA-DQB1*0302
Collection Method: Buccal (Cheek) Swab
- Free shipping both ways
- Easy-to-use cheek swabs
- AABB, ISO17025 & CLIA accredited lab
Product Description
How It Works
| STEP 1: Purchase Your Kit | STEP 2: Collect DNA Samples | STEP 3: Mail Samples to Lab | STEP 4: Receive Your Results |
|---|---|---|---|
Your kit will be delivered to your doorstep within days with free nationwide shipping. |
Collect painless mouth swab samples at home with the included materials. |
Mail the samples to the lab using the prepaid shipping envelope. |
Get your results online within 1-2 business days after testing begins. |
Find out if you are at increased risk of developing celiac disease
Celiac disease is an autoimmune disorder in response to the digestion of gluten. Gluten is a protein found in wheat, barley, rye and other grains and is commonly included in many processed and packaged foods. When an affected individual consumes a gluten-containing product, their immune system reacts aberrantly and damages the lining of their small intestine. This severe damage to the villi of the intestine prevents the absorption of vitamins, minerals and nutrients and leads to serious problems.
What are the HLA-DQA1 and HLA-DQB1 Genes?
There are more than 200 HLA genes, which are located on chromosome 6 and encode components of the human leukocyte antigen (HLA) complex. The HLA complex is an important part of the immune system, helping distinguish between harmless proteins (from self, diet or environment) and harmful foreign proteins from viruses and bacteria. The protein encoded by the HLA-DQA1 and HLA-DQB1 genes form a complex together to display foreign proteins to the immune system in order to trigger a response against the foreign invader. This HLA-DQA1 + HLA-DQB1 complex is also important to develop self-tolerance in children. However, in celiac-affected people, this complex also binds to and displays the harmless gliadin fraction from gluten, initiating an aberrant immune response.
Age Limit: None. This test can be taken at any age.
Collection Method: Buccal swabs. The test kit contains buccal swabs and instructions for collecting a buccal swab sample from inside the mouth.
Alleles Identified: HLA-DQA1*05 HLA-DQB1*02 HLA-DQB1*0302
Testing Methodology: Sequence Based Typing (SBT)
Kit Expiry: DNA test kits do not have an expiry date and can be used at any time. Once the DNA sample is collected, it must be returned to the laboratory for testing within three months of collection. No refrigeration is required. Store at room temperature.
Limitations It is important to remember that the presence of one or more of these at-risk alleles (HLA-DQA1*05, HLA-DQB1*02, HLA-DQB1*0302) does not mean that an individual will definitely develop celiac disease. Each allele does increase the risk but there are many individuals that have these alleles and never develop celiac disease. Alleles other that HLA-DQA1*05, HLA-DQB1*02 and HLA-DQB1*0302 will not be identified. An increased risk of celiac disease and an accurate diagnosis are also dependent on a variety of genetic and non-genetic factors that are not detected by this assay.
Here are the answers to the most frequently asked questions about this test.
Are my results confidential?
Yes, your results are 100% confidential. No one will be able to access your account or your results unless you give them your confidential account login. You can change the password to your account at any time. Please remember to safeguard your login information and not share it with anyone.
How long does the test take?
Testing begins immediately the day that your samples arrive at the laboratory. In some special situations, additional testing may be required, which could increase the turnaround time by a few extra days. You can check the status of your test online 24/7 using your secure account login. Your test report is released immediately once testing is complete.
Would eating or drinking before collecting my DNA affect my results?
Drinking or eating will not change the results in any way. The reason that you are not supposed to drink or have anything in the mouth for an extended period prior to collection is to ensure that we have enough buccal cells to complete the test. If there are not enough cells to complete the test, then the results will not be released and a recollection will be required.
How do I ship my samples back to the laboratory?
Once you have finished your sample collection, place the collection kit box into the prepaid plastic USPS envelope included with the kit, then mail your samples to the laboratory via your mailbox or a local USPS drop box. If you wish to monitor the status of your shipment, remember to record the tracking number on the shipping label. You can track the status of your shipment using your tracking number on the USPS website.
Do I have to use the return envelope to send my kits back?
No. You can send the kits back to the laboratory using any shipping method of your choosing. Please be advised that if you do not use the included prepaid return mailer to ship your samples, it is your responsibility to ensure that your samples arrive at the laboratory. We will not be able to provide assistance for shipments that do not use our prepaid return mailer.
Reviews(14)
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Isaac Z.
(verified owner)This test kit made everything so easy. The instructions were clear, and the results were fast.
Tyler H.
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Ashley K.
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(verified owner)I’m very impressed with how easy it was to use the test kit. The results were delivered faster than I expected.
Daniel Y.
(verified owner)I’m very satisfied with the test kit. It was easy to use, and the results were clear and accurate.