Genetrace Cardiovascular Disease (ApoE) DNA Test
$194.99$214.99
The APOE gene affects both your risk of a heart attack and the most effective way to lower your cholesterol levels. Discover your risk and find the best treatment option for you.
- Free shipping both ways
- Easy-to-use cheek swabs
- AABB, ISO17025 & CLIA accredited lab
Product Description
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How It Works
| STEP 1: Purchase Your Kit | STEP 2: Collect DNA Samples | STEP 3: Mail Samples to Lab | STEP 4: Receive Your Results |
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Your kit will be delivered to your doorstep within days with free nationwide shipping. |
Collect painless mouth swab samples at home with the included materials. |
Mail the samples to the lab using the prepaid shipping envelope. |
Get your results online within 1-2 business days after testing begins. |
Cardiovascular disease (CVD) is responsible for approximately 1 in 5 deaths in the US. CVD is an umbrella term that captures heart attacks, strokes, chest pain and angina, all of which are caused by the narrowing or blockage of blood vessels. Many factors such as diet, activity level, age, weight, and genetics can contribute to an individual’s risk of CVD. The APOE gene is the best genetic predictor for whether an individual will respond to statins or changes in their diet to lower cholesterol levels.
The main function of ApoE (the protein product of the APOE gene) is to help clear cholesterol and triglycerides from the bloodstream by moving them into cells. There are at least three slightly different versions or alleles of this gene, each producing a slightly different version of the ApoE protein. An individual’s susceptibility to health conditions like CVD depends on the combination of specific genetic variants they have inherited.
What is tested?
This test detects variants of the APOE gene linked to an increased risk of cardiovascular disease (CVD). We each inherit two copies of the APOE gene, one from each parent. Studies linked the following variant combinations to increased risk of CVD.
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Two copies of the e3 allele: Not at increased risk CVD
One e3 allele and one e2 allele: Not at increased risk of CVD
Two copies of the e2 allele: Lower LDL-cholesterol, but increased risk of hyperlipoproteinemia type III, which can contribute towards CVD
One or two copies of the e4 allele: Elevated LDL-cholesterol and increased risk of CVD
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Studies have also linked APOE variants to an individual’s ability to lower cholesterol levels through diet and statins (cholesterol-lowering medications).
APOE e3/e4 or e4/e4:
Individuals with these variant combinations should consume a low-fat diet as they are unable to metabolise fats effectively. These individuals also do not respond to statins.
APOE e2/e2 or e2/e3:
Individuals with these APOE combination are less effective at metabolizing carbohydrates. They are able to metabolize fats and respond better to statins.
Here are the answers to the most frequently asked questions about this test.
Are my results confidential?
Yes, your results are 100% confidential. No one will be able to access your account or your results unless you give them your confidential account login. You can change the password to your account at any time. Please remember to safeguard your login information and not share it with anyone.
How long does the test take?
Testing begins immediately the day that your samples arrive at the laboratory. In some special situations, additional testing may be required, which could increase the turnaround time by a few extra days. You can check the status of your test online 24/7 using your secure account login. Your test report is released immediately once testing is complete.
Would eating or drinking before collecting my DNA affect my results?
Drinking or eating will not change the results in any way. The reason that you are not supposed to drink or have anything in the mouth for an extended period prior to collection is to ensure that we have enough buccal cells to complete the test. If there are not enough cells to complete the test, then the results will not be released and a recollection will be required.
How do I ship my samples back to the laboratory?
Once you have finished your sample collection, place the collection kit box into the prepaid plastic USPS envelope included with the kit, then mail your samples to the laboratory via your mailbox or a local USPS drop box. If you wish to monitor the status of your shipment, remember to record the tracking number on the shipping label. You can track the status of your shipment using your tracking number on the USPS website.
Do I have to use the return envelope to send my kits back?
No. You can send the kits back to the laboratory using any shipping method of your choosing. Please be advised that if you do not use the included prepaid return mailer to ship your samples, it is your responsibility to ensure that your samples arrive at the laboratory. We will not be able to provide assistance for shipments that do not use our prepaid return mailer.
Reviews(14)
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Joshua V.
(verified owner)This test kit was exactly what I needed. It was quick, easy, and accurate.
Stella V.
(verified owner)I was very impressed with the speed and accuracy of the results. The test kit was simple and efficient.
Brian Z.
(verified owner)The test kit arrived quickly, and the instructions were easy to follow. I got the results in no time.
Zachary X.
(verified owner)The whole process was quick and efficient. I received the results faster than I thought, and they were very accurate.
Michelle Q.
(verified owner)The test kit was straightforward and easy to use. The results were accurate, and I got them quickly.
George R.
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Owen M.
(verified owner)The test kit was very user-friendly, and the results were delivered faster than I thought.
Richard O.
(verified owner)The test kit was easy to use, and the results came back very quickly. I couldn’t ask for a better experience.
Allison C.
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Elizabeth M.
(verified owner)I was very happy with how fast the results came back from the test kit. It was a very simple process.
Stella V.
(verified owner)I was a little nervous about using the test kit, but it turned out to be very simple and stress-free.
Hazel K.
(verified owner)I appreciated how easy it was to use the test kit. The results were fast and accurate.
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(verified owner)This test kit was a great value. It was easy to use, and the results were very detailed.
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